Sedatives include a large group of drugs that slow down brain activity, causing relaxation and drowsiness.This group includes all known means, which are sold without a prescription, such as valerian, and small and large tranquilizers such as lepomepromazin.
Sedatives depress the central nervous system, in most cases, affect one of its major neyromediantorov - gamma-aminobutyric acid (GABA).Neurotransmitters or neurotransmitters - are substances which carry communication between brain cells.Although various types of sedatives act on their own, ultimately it is their ability to increase GABA activity leads to relaxation of the person.
The higher the activity of GABA, the stronger would be a soothing effect.Since the sedatives cause drowsiness, they are encouraged to take not only in anxiety and increased excitability, and insomnia.They also take people who suffer from panic attacks and other disorders that cause uncontrollable fear.
believed that at present the majority of cases of abuse of drug
Sedatives in one form or another have been used in ancient times.Almost every culture have been known certain plants, has a calming effect (for example, valerian, which is discussed separately).During the years of trial and error, scientists have found exactly what plants, and in what doses to be used.Some are dried and used for making tea, other prepared tinctures, lotions, and so forth.With them they were treated as anxiety and insomnia, and tried to relieve the symptoms of severe mental disorders.
We can only guess how many people are affected and how, before the doctor scientist of antiquity was able to understand at least something which parts of the plant should be used as sedatives.Be that as it may, the natural medicines discovered thousands of years ago, we use to this day, and use them to create new drugs.So, the first modern drug from the group of major tranquilizers was obtained from the plant Rauwolfia serpentina (Rauwolfia serpentina), is in India for centuries is used for snake bites (hence the name), as well as some mental disorders.In the mid-20th century American scientists undertook a study of this plant, and soon discovered that one of its active ingredients - reserpine, can be successfully used in the treatment of high blood pressure, as well as schizophrenia and other mental illnesses Mental illness - ashamed to ask forhelp? .
first synthetic small tranquilizers, as well as first analogs vegetable sedatives such as valerian or lavender healing properties of lavender - not only pleasant aroma , steel bromides, which began to synthesize in the 1860s.However, because of the serious side effects of these drugs have not won a special popularity.In 1903 came the first barbiruraty - they are very effectively cope with anxiety Anxiety - how to distinguish normal from disease? and insomnia, but quickly causes dependence.In addition, an overdose of barbiturates often led to the death of patients.Fairly soon, scientists have developed the first class of drugs benzodiazepines - they have fewer side effects, in contrast to barbiturates, they induce dependence in long-term use only.
Tranquilizers large and small
Among the many sedatives are the two large groups of products: large and small tranquilizers.First used to treat severe mental disorders such as schizophrenia and psychosis.The drugs alleviate the symptoms of these diseases, although, of course, can not cure them completely.Minor tranquilizers prescribed for insomnia, anxiety disorders, panic attacks and and a number of other disorders.Barbiturates and benzodiazepines are a group of minor tranquilizers.Almost all of tranquilizers in most countries of the world are sold by prescription, and during the course of treatment, the doctor must constantly monitor the condition of the patient.This helps reduce the likelihood of addiction and other complications.
valerian and other herbal sedatives
Valerian used as a sedative in ancient Greece.We wrote about it in his writings of Hippocrates and Galen.It was very popular in the Middle Ages when it was used for the treatment of nervous diseases, heart palpitations, tremor.Valerian is widely used today.It has been established that it is not only by itself has a soothing effect, but also enhances the effect of other sedatives and hypnotics.At the same time, she, like many other sedatives, reduces concentration and reduces the rate of reaction, and it is sure to keep in mind for those who accept it.
Schisandra - another natural sedative, which is sometimes called the Chinese Prozac.It has long been used in traditional Chinese medicine Traditional Chinese medicine and treatment of problem skin , and today the capsule on the basis of this plant can be purchased in many other countries.
Lavender - a sedative, has a very soft, but stable effect.It calms aroma of this plant, so aromatherapy using lavender essential oil can be not only pleasant, but also very useful.
Red Clover, strictly speaking, not a sedative.But this plant - a rich source of minerals, its active substances thin the blood and stabilize the work of many body systems.Acceptance of red clover in combination with herbal sedatives helps to achieve a deeper and more lasting effect.The only restriction: red clover can not be used by pregnant women and those who take medications, blood thinning.