Sibutramine - effective but not safe

  • Sibutramine - effective but not safe
  • appetite regulation system

Sibutramine Sibutramine is used for the treatment of obesity in conjunction with a low calorie diet.This drug is an aid to those who adhere to a rigid diet - its main effect is that it regulates the activity of brain chemicals that are responsible for feelings of hunger.


  • allergy to any component of sibutramine
  • Eating disorders (anorexia, bulimia)
  • Uncontrolled and / or severe hypertension
  • High blood pressure in the lungs
  • presence in the personal historythe following diseases: heart disease and cardiovascular system (rapid or irregular heartbeat, heart attack, heart failure, hardening of the blood vessels, poor circulation in the legs), stroke or transient ischemic attack (TIA or mini-stroke)
  • serious liver or kidney disease
  • you are taking selective serotonin reuptake inhibitors (eg fluoxetine), other drugs that suppress appetite, or monoamine oxidase inhibitors (eg, phenelzine).Be sure to tell your doctor if you are taking any of these drugs
  • Age over 65 years

In addition, before taking sibutramine should inform your doctor if you are pregnant or plan to become pregnant in the near future, if you have had an allergic reaction toany drugs and / or if you have ever had depression Depression - a little more than a bad mood Depression - a little more than a bad mood or other mental disorders.

Drug Interactions

The following drugs should not take simultaneously with sibutramine: dextromethorphan, dihydroergotamine, antifungal drugs, which include antifungals (eg, itraconazole, ketoconazole), lithium, MAO inhibitors (eg, phenelzine)narcotic analgesics (e.g., codeine, fentanyl, meperidine), pentazocine, agonists of serotonin 5-HT1-receptors (e.g., sumatriptan), SSRI (e.g., fluoxetine), or tryptophan.They increase the risk of side effects of sibutramine, some of which may be life-threatening.

ephedrine or pseudoephedrine may also contribute to the manifestation of the side effects of sibutramine, especially such as increased blood pressure and increased heart rate.

Anticoagulants in combination with sibutramine increases the risk of bleeding.

How to receive sibutramine

Sibutramine can be taken with food or between meals.

As a rule, it is recommended to take the drug in the morning to avoid sleep disturbances Dreams: how to understand our dreams Dreams: how to understand our dreams .If you forget to take sibutramine time, do not double the dose and continue to take the medicine as usual.

Additional information about the drug

Sibutramine may cause dizziness Dizziness - if the ground is slipping from under his feet Dizziness - if the ground is slipping from under his feet and / or blurred visible objects.This effect is compounded when alcohol and some drugs.It can also negatively affect your ability to drive a vehicle.

While receiving sibutramine should abandon the use of alcohol and drugs that cause drowsiness.

change in dietary habits and physical activity are the most important part of a weight reduction program.

order not to gain weight shortly after receiving sibutramine and maintain a healthy weight throughout life, should always adhere to the rules of a healthy lifestyle.

Serotonin syndrome and neuroleptic malignant syndrome is a rare and very serious possible complications sibutramine.Symptoms of these conditions include agitation, increased anxiety anxiety - how to distinguish normal from disease? Anxiety - how to distinguish normal from disease? , fever, tremors, sweating, diarrhea, nausea, vomiting, rapid and / or irregular heartbeat, coma.When any of these symptoms should immediately seek medical help.

During the course of treatment with sibutramine, and for some time after it is necessary to undergo regular medical examinations to monitor the reduction of weight and general health of the patient.

During the course of treatment should use effective contraception as this drug may adversely affect the development of the fetus, if the pregnancy occurs during therapy.

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