cytomegalovirus - a type of herpes virus (human herpes virus type V).The disease, which causes the virus, called cytomegalovirus.It was first described in the late 19th century, but only in the second half of the 20th century, it was identified the pathogen.
Tsitomegliya - a viral disease characterized by lesions of the salivary glands, and other organs to form in the tissues of giant cells with large intranuclear inclusions.
There are localized and generalized forms of cytomegalovirus.At the localized form, which usually develops in adults and children older than three months, affects the salivary glands.Generalized form is often innate and develops before the age of three months, but can also occur in older children and adults.In the pathological process involved many organs.
localized form of cytomegalovirus infection with lesions of the salivary glands is usually asymptomatic.But a sharp decline in immunity (the newborn, infants and immunocompromised adults) it ca
Generalized form of cytomegalovirus infection manifests itself in different ways depending on the patient's age, the state of his immunity and the pre-emptive destruction of an organ.
particularly difficult disease occurs in newborns.Symptoms of cytomegalovirus have a progressive jaundice, enlarged liver and spleen, severe hemolytic (destruction of red blood cells with) anemia, hemorrhages in the skin, reducing the number of platelets in the blood, tendency to bleed and hemorrhage (hemorrhagic diathesis).
amazing and the central nervous system, which is manifested by repeated convulsions due to the development of viral meningoencephalitis.Such children are often born with microcephaly (a decrease in volume of the brain), and hydrocephalus (water on the brain).Later they going mental retardation or mental retardation Mental retardation - if the mind is underdeveloped .The defeat of the body is manifested in the form of chorioretinitis (inflammation of the choroid and retina), cataract Cataracts - how to solve the problem completely? (lens opacities), optic neuritis.Defeat hearing snarusheniyami from the auditory nerve can lead to deafness.
If infection spreads to the respiratory system, the children appear persistent cough, shortness of breath and other symptoms of interstitial (with the defeat of the interstitial lung tissue) pneumonia.Such lesions may join secondary bacterial infection with the development of pleurisy (inflammation of the serous membrane covering the lungs) and sepsis (blood poisoning).
very hard for cytomegalovirus infection in children occurs when joining other childhood infections such as measles Measles in children - may cause serious complications , chicken pox and other diseases.It is also distressing to cytomegaly newborns with cystic fibrosis Cystic fibrosis : early diagnosis - the key to recovery - congenital disease characterized by lesions of all the organs that produce mucus.
In developing kidney interstitial nephritis, which is often asymptomatic, and only when the laboratory examination of urine can detect traces of the destruction of the body.
With the defeat of the digestive system in children developing frequent vomiting, loose stools, decreased enzyme activity in the duodenum.When CMV can also affect the endocrine glands.
In congenital CMV infection is often observed stillbirth or neonatal death.
older children generalized form shown enlarged liver, jaundice, acute liver failure, prolonged fever, anemia, changes in laboratory parameters of blood.Also, in older children and adults, CMV infection can occur by type mononuclear syndrome with inflammatory changes in the throat, enlarged cervical lymph nodes, liver and spleen.
Pregnancy and tsitmegalovirusnaya infection
Cytomegalovirus infection is the biggest danger to the fetus and newborn child.Especially dangerous is the primary infection with cytomegalovirus during pregnancy.
Therefore, all pregnant women screened for cytomegalovirus.We study the blood where cytomegalovirus and revealed the presence of antibodies to them, and such a study is conducted twice: at the beginning of pregnancy and in the third trimester, shortly before the birth.
Cytomegalovirus is transmitted from mother to child is not always, in the case of primary infection during pregnancy are infected nine children out of a hundred, and if the mother has been infected by this infection before pregnancy, it is transmitted to each thousandth child.