The rate of uric acid in the blood - the importance of correct concentration
Uric acid - a substance that is formed when the body breaks down chemicals called purines.Purines are found in many foods and beverages, such as the liver, anchovy, mackerel, beans and peas, beer.What is the rate of uric acid in the blood, and can talk about high and low concentration of this substance?
Most uric acid dissolves in the blood, and then enters the kidneys and excreted in the urine.In some cases, however, the body produces too much uric acid, or may not display it quickly enough.This can cause various health problems.
When assigned analysis on the level of uric acid in the blood?
As a rule, such an analysis is prescribed for gout is suspected, and some kidney diseases.Your doctor may also recommend to do this analysis, if the patient was treated by some potent medicines and / or it has sharply decreased weight.
What is the rate of uric acid in the blood?
adult male normal concentration of uric acid in the blood ranges from 3.4 to 7 mg / dl in adult women - from 2.4 to 6 mg / dL.The rate for children - 2-5.5 mg / dl.The crystals of uric acid in the joints (which is typical for gout) can be formed even if its level is lower than 7 mg / dl.
What are deviations from the norm?
level of uric acid in the blood may depend on the individual.Thus, some otherwise healthy people its concentration normally somewhat higher (or lower) than that of most of the members of the same age group.In many cases, however, too high or low levels of uric acid is a sign of certain health problems.
Elevated levels of uric acid in the blood can indicate the following violations:
- Alcoholism Diabetes Gout
The most characteristic symptom of this disease is severe, sudden pain in one or more joints.Most often there is pain in the joints Joint pain - how to understand what is going on? big toes.In many patients, the symptoms of gout occur at night, although in general it can occur at any time of the day.Other possible symptoms of gout: an extremely high sensitivity of the joints of patients, so that any touching them causes pain, swelling and inflammation in the joints, reddish, shiny skin on the surface of the patient's joint, peeling skin and severe itching.In severe cases, patients with gout becomes hard to walk, and even a little pressure - for example, when a person is covered by a blanket - causes severe pain.
- Hypoparathyroidism - a disease that affects the parathyroid glands
There are four, and they are located next to the thyroid gland.These glands help control calcium use by the body.When hypoparathyroidism parathyroid hormone levels become too low, the level of calcium in the blood is reduced, and the concentration of phosphorus increases.The most common cause of damage is hypoparathyroidism parathyroid glands during surgery.Sometimes the development of the disease results in the treatment of hyperthyroidism with radioactive iodine, too low magnesium in the blood and autoimmune disorders.The symptoms of hypoparathyroidism may be abdominal pain, brittle nails, cataracts Cataracts - how to solve the problem completely? , dry hair How to prevent and eliminate dry hair - a few simple tips , dry and scaly skin, muscle spasms, pain in the legs, painful menstruation, tingling in the lips, fingers and toes, problems with tooth enamel(in children).
- Lead poisoning
Symptoms of lead poisoning can be a pain and abdominal cramps, aggressive behavior, anemia, constipation, sleep problems, headaches, irritability, poor appetite, tiredness.Especially dangerous is lead poisoning for young children, and the younger the child is, the more dangerous it is.Exposure to lead can lead to problems with behavior and concentration, poor learning, hearing problems, kidney damage, stunted growth.With a very strong lead poisoning in both children and adults may experience symptoms such as vomiting, uncertain, stumbling gait, muscle weakness, convulsions and coma.
- Kidney stones
If elevated levels of uric acid in the blood caused by kidney stones, the patient may experience symptoms such as blood in the urine, chills, fever, nausea, vomiting, pain in the left or right side of the waist,pain in the groin, or the testicles.
- Polycythemia vera
is a malignant disease that affects the bone marrow, which leads to an increase in the number of blood cells, the most - red blood cells.It is a rare disease that is more common in men than in women and is most common in people older than forty years.Its symptoms include: shortness of breath when a person is in a horizontal position, dizziness, feeling of pressure in the left upper abdomen (due to an enlarged spleen), headache, itching, especially after a warm bath or shower, redness of the skin - oftenon the face, shortness of breath, bluish color of the skin, fatigue, vision problems.
- Abuse of products with a high concentration of purines
- Renal failure
dangerous disorder that can lead to serious health consequences.Among its symptoms - the presence of blood in the stool, bad breath, metallic taste in the mouth metallic taste in the mouth - what causes and how to get rid of? , change in mental status or mood swings, loss of appetite, decreased sensitivity of the hands and feet, fatigue, hand tremors, increased blood pressure, nausea and vomiting that can last for several days, epistaxis, hiccup, continues fora long time, seizures, shortness of breath, swelling, problems with urination.
uric acid levels in the blood below normal may be a sign of the following violations:
- Fanconi syndrome - a congenital disorder that affects the functioning of the renal tubules.In this disease, a number of substances that normally should fall from the kidneys into the bloodstream, instead excreted in the urine.Sometimes this disorder occurs in adults, for example, as a result of certain medications, renal transplant, undergoing multiple myeloma or primary amyloidosis.Signs of Fanconi's syndrome are usually pain and aching in the bones weak and very intense urination, which can cause dehydration;
- Wilson's disease - a hereditary disease in which the body can not properly process the copper, and it accumulates in the body in very large quantities.The excess of copper causes damage to the liver and nervous system.Wilson's disease is rare;If both parents have the genes responsible for the inheritance of the disease, the likelihood that it will develop in a child with each pregnancy is 25%.Wilson disease symptoms are shortness of movement of the hands and feet, abnormal position of the limbs, difficulty walking, emotional and behavioral problems, speech problems, weakness, tremor of limbs, involuntary movements, the presence of blood in vomit;
- syndrome of inappropriate antidiuretic hormone secretion, or the syndrome of inappropriate secretion of antidiuretic hormone.It is a rare disorder in which the body produces insufficient amounts of the hormone, which helps control the output of fluid through the kidney.The syndrome Parhona decrease sodium levels in the blood - hyponatremia.Most often it is a violation of people diagnosed with heart failure or brain injuries that affect the hypothalamus.Other causes of the syndrome can be Parhona: lung cancer, encephalitis, meningitis, brain tumors, Guillain - Barre syndrome, thyroid hormone deficiency or parathyroid.The most common symptoms of the disease - nausea, vomiting, convulsions, tremor, depression, memory problems, confusion, in some cases - hallucinations and coma.