Antiphospholipid syndrome - a dangerous autoimmune reactions
- Antiphospholipid syndrome - a dangerous autoimmune reactions
- Phospholipids and their role in the human body
Antiphospholipid syndrome - a disorder in which the immune system mistakenly produces antibodiesto combat with some normal blood supply.This can lead to the formation of clots in blood vessels, and various complications of pregnancy such as miscarriage and stillbirth.
Symptoms The most common symptoms of antiphospholipid syndrome are:
- formation of blood clots in the veins of the legs (deep vein thrombosis);sometimes they travel to the lungs, resulting in pulmonary embolism develops.
- Repeated miscarriages or stillbirth and other pregnancy complications such as premature birth and high blood pressure in pregnancy (pre-eclampsia).
Other symptoms of antiphospholipid syndrome are much rarer:
- Neurological symptoms
example, chronic headaches, dementia and seizures that may occurdue to the fact that blood clots penetrate into some part of the brain.
Some patients on the hands and knees rash, pattern reminiscent of the network.
- Cardiovascular disease
Among patients with antiphospholipid syndrome are often found various violations related to heart valve.
bleeding in some patients reduced levels of blood platelets - the cells that due to which blood can clot.This condition is called thrombocytopenia.In mild forms, it has virtually no symptoms, but if the platelet count is too low, there may be episodes of epistaxis and bleeding from the gums.It also happens bleeding under the skin, because of what appear reddish spots that resemble bruises.
extremely rare in antiphospholipid syndrome symptoms such as uncontrolled movements of the limbs, memory loss, sudden hearing loss, depression Depression - a little more than a bad mood or psychosis.
When should you see a doctor
- pain or swelling of the extremities.Please contact to the doctor if the veins in the hands or feet increased, redden, become painful.If the pain is severe and is accompanied by fever, call an ambulance.This, as well as chest pain Chest pain: one symptom - a lot of diseases and expectoration of sputum with blood may be symptoms of thromboembolism Thromboembolism: Severe complications pulmonary artery
- vaginal bleeding during pregnancy.This may be a sign of miscarriage Miscarriage - whether it can be insured? .
- seek immediate medical help if you have any symptoms of a stroke such as sudden numbness, weakness, paralysis mud face, hands or feet;difficulty using and understanding speech;blurred vision;severe headache and dizziness.
in antiphospholipid syndrome, the immune system damages the proteins that bind phospholipids - fats that are present in the blood and it is very important for normal clotting.There are two main types of phospholipid syndrome:
- Primary.If the patient has other autoimmune disorders such as systemic lupus, then a primary phospholipid syndrome.
- secondary antiphospholipid syndrome seen in patients who already have any autoimmune diseases.In this case, the cause of the syndrome is considered to be the primary autoimmune disorder.
can not say exactly why developing primary antiphospholipid syndrome, but it is assumed that the production of antibodies may be affected by the following factors:
- Antiphospholipid syndrome is more common in people with syphilis, HIV, hepatitis C, malaria and other diseasesthan in healthy people.
Gidralizin (a drug for high blood pressure), quinidine (a medicine used to regulate the heart rhythm), antispasmodic phenytoin (Dilantin), and the antibiotic amoxicillin increases the risk of antiphospholipid syndrome.
Antiphospholipid syndrome is not hereditary, but scientists have found that the most likely to develop this disorder in people, in whose family history has this syndrome.