One of the modern effective antifungal drugs is orungal.Side effects in orungala are fairly common, it is a characteristic of antifungal drugs.That is why the treatment of fungal infections should only be prescribed by a doctor.
main action orungala
Orungal - a modern anti-fungal drug, the active substance is itraconazole.After oral itraconazole actively absorbed from the gastrointestinal tract, the blood flows initially and then to the tissue.Feature orungala is that its active substance accumulates in the tissues in much higher concentration than in the blood.
entered the tissue affected by pathogenic fungi, inhibits the synthesis of ergosterol orungal - biologically active substance, a component of cell membranes of fungi, it leads to the destruction of fungal cells.
orungal displayed in the faeces and urine, after decomposing in the liver to metabolites.Overall orungal drug is not toxic and is generally well tolerated.But in this case, when it is assigned to a physician taking into
side effects of cardiovascular
orungala Side effects from the cardiovascular system are rare and mainly inPatients who have had treatment to some problems with the circulatory system.It is also relatively common side effects occur in elderly patients.
fact that orungal can cause negative inotropic effects, ie to reduce the force of cardiac contractility.This leads to a stagnation of blood in the systemic and pulmonary circulation.Stagnation in the systemic circulation - is swelling and impaired function of internal organs.The stagnation in the pulmonary circulation - a shortness of breath and a threat to the development of pulmonary edema.
side effects from the digestive organs
Sometimes when taking orungala appear side effects such as nausea, vomiting, diarrhea, mild abdominal pain Abdominal pain: Types and Symptoms .They usually do not require discontinuation of the drug and tested independently.
But if there were pains in the right upper quadrant or liver problems, which may appear light yellow skin and sclera, and can - only changes in the laboratory analyzes, the orungal usually overturned.This must be done, as there are isolated cases of toxic hepatitis Toxic hepatitis - the impact of harmful substances on the liver patients receiving orungal.
side effects from the other organs and systems
Orungal rarely has side effects in the nervous system.It headaches, dizziness, and sometimes - neuritis or neuralgia of peripheral nerves.
Women orungal can cause transitory menstrual irregularities.Perhaps the loss of hair, of course, possible allergic reactions: urticaria, angioedema, anaphylactic shock, Stevens - Johnson (severe allergic mucous membranes, including the internal organs), etc.
Can orungal have a negative impact on pregnant women and nursing mothers
Orungal not recommended during pregnancy.There is evidence that the intake of this drug in the fetus develop various congenital anomalies.At the same time, reliable data that these anomalies are connected with the reception orungala rather than to the impact of any other factor not.
also found that intermittent reception orungala about vulvovaginal candidiasis (thrush) side effects did not cause the fetus.Therefore orungal not recommended for pregnant women, but at the same time its application for health (life-threatening diseases) can not be excluded.In this case, orungal prescribed if the expected positive effects from the body of the mother than the potential risk to the fetus.
During feeding baby Breastfeeding - a personal choice breast orungal not prescribed, as it stands with human milk.If the purpose of the drug is necessary, it is recommended to interrupt breastfeeding.
young woman during the course of treatment orungalom Orungal - antifungal broad spectrum methods of contraception should be used at all times during and after the treatment before the onset of the first menstrual period after treatment.
Orungal - a modern, effective anti-fungal medication.Compared with other antifungals it gives not so many side effects and is generally well tolerated.But in this case orungal prescribed by a doctor with all the indications and contraindications.Separate application orungala may have undesirable effects