amitriptyline - a medication with a strong psychoactive effect.He has a lot of contraindications for the appointment and side effects, so appoint a doctor.Self-administration of amitriptyline can lead to overdose, and it is life-threatening.
Why overdose of amitriptyline dangerous
Amitriptyline increases or inhibits the action of different mediators - biologically active substances that transmit information through the nervous system arousal.How to increase and decrease the action of these substances have a significant effect on the body and especially on the vital organs - the brain and the cardiovascular system.
Amitriptalin one of the first antidepressants, so he has a lot of side effects and even a small overdose can cause drug poisoning.
Today, the pharmaceutical industry produces mainly selective antidepressants that do not have so many side effects and are therefore safer.
How to take amitriptyline
Amitriptyline is used only on a doctor's prescript
Take amitriptyline inside during or after eating.Initially assigned a small dose of the drug, as the body has to adapt to its reception.At the beginning of taking this drug is its anticholinergic (inhibitory effect of the neurotransmitter acetylcholine) action in the form of a stable mydriasis and related blurred vision, increased intraocular pressure, dry mouth, suppression of motor activity of smooth muscles of internal organs (it appears constipation and urinary retention), fever.
But over time, all these phenomena (or most of them) are what allows you to gradually increase the dose to 150-200 mg per day.In this day the drug is taken at a lower dose, and at night - more.Sometimes, treatment is initiated with intramuscular administration of amitriptyline, and then move on to receive it inside.The treatment is usually a long, persistent antidepressant effect appears not earlier than two weeks after starting the drug, but if within a month the patient's condition does not improve, drug overturned.The duration of treatment is determined by your doctor.You will cancel
amitriptyline gradually, otherwise may develop withdrawal symptoms of headache, nausea, vomiting, diarrhea, irritability Irritability - Try to control your mood , passing sometimes in aggressive, intimidating appearance Dreams Dreams: howunderstand our dreams and so on.
when there may be signs of overdose of amitriptyline
tolerated dose of amitriptyline for each individual patient.In the outpatient setting may be receiving 150 mg daily (6 tablets of 25 mg), and in the hospital where the patient is under the clock surveillance - 300 mg per day.
At higher daily doses may be signs of overdose, which appear lethargy, drowsiness, confusion (but sometimes it is combined with bouts of emotional and motor excitation), persistent mydriasis, disturbance of thermoregulation in the form of fever, vomiting.
respiratory disorders may occur in the form of its oppression, violation of the pronunciation of individual sounds, syllables and words (dysarthria), hallucinations (patients see, hear and feel what is actually there), seizures, persistent tension (stiffness) of the skeletal muscles,impairment of consciousness up to coma.With increasing signs of an overdose of growing changes in the cardiovascular system in the form of cardiac arrhythmias, lowering blood pressure to alarming numbers and signs of heart failure Heart failure - when the heart is unable to cope with the work .
What if I overdose
very dangerous overdose of amitriptyline in the outpatient setting.In such cases, you should immediately call an ambulance.In the meantime, the ambulance rides, the patient must be flushed through the stomach and give a few tablets of activated charcoal Activated carbon - old but indispensable , which adsorbs on the surface of the drug residues and remove them from the body naturally.
Most often these patients have to be hospitalized and to provide medical care in a hospital: intravenously injected a large amount of liquid with which amitriptyline gradually washed out of the body.
It should be the condition of the patient and, if necessary, symptomatic treatment.
Amitriptyline dangerous to take on their own, especially at high doses and for a long time.