Amitriptyline - help with major depression

  • Amitriptyline - helps with strong
  • Depression What is depression and why it occurs

Amitriptyline Amitriptyline belongs to medicines from the group of tricyclic antidepressants.This drug works by affecting the nerve cells in the brain.In the brain there are many various chemical compounds called neurotransmitters.They are a kind of chemical transmitters of messages between nerve cells.Serotonin and noradrenaline are among neurotransmitters.

How does amitriptyline?

When serotonin and noradrenaline are released from nerve cells in the brain, a person's mood improves.When these neurotransmitters again absorbed into cells, they no longer affect mood.It is assumed that, when a person has become depressed, the volume of serotonin and norepinephrine released into the brain is significantly reduced.

amitriptyline prevents the reabsorption of serotonin and norepinephrine in the nerve cells of the brain.Thus, the drug relieves symptoms of depression Depression - a little more than a bad mood Depression - a little more than a bad mood .

One of the most common symptoms of amitriptyline is somnolence, therefore it is most effective for people who suffer from depression, along with sleep disorders Dreams: how to understand ourDreams Dreams: how to understand our dreams and / or increased anxiety anxiety - how to distinguish normal from disease? Anxiety - how to distinguish normal from disease? .

effects of amitriptyline become apparent only after 3-4 weeks after the start of reception, so it is important to continue taking it even if you do not see any results.If you feel that depression is compounded, for example, if you have any extremely pessimistic and / or suicidal thoughts, you should immediately talk to your doctor.

In some cases, amitriptyline is used to treat bedwetting in children.The drug blocks the cholinergic receptors which are located on the surface of the muscle cells of the bladder wall.This prevents a substance called acetylcholine act on these receptors.Acetylcholine normally causes a reduction in the walls of the bladder and emptying.Limiting its activity reduces the likelihood of involuntary contraction of the bladder walls.For such therapy amitriptyline can use no more than three months.

Furthermore, amitriptyline may be used to prevent and treat migraine pain nerve.


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Amitriptyline is not recommended for the treatment of depression in patients under 16 years of age and for the treatment of bedwetting in children under 6 years.

If there are any signs of an allergic reaction to the drug should immediately stop taking and consult your doctor.


Because amitriptyline causes drowsiness, regardless of how much you relax during the course of treatment should avoid driving vehicles.In addition, while you are taking amitriptyline, better to give up alcohol or reduce its consumption to a minimum, because it may increase drowsiness.

Reception amitriptyline can lead to a sharp decrease in blood pressure when you stand up - because it often begins to feel dizzy and dark eyes.This side effect is observed only at the beginning of treatment.

Antidepressants often cause a reduction in sodium levels in the blood - a condition called hyponatremia.This is one of the reasons for sleepiness, and may also cause transient dizziness, muscle spasms and convulsions.Older people are particularly vulnerable to such action of antidepressants.

Do not abruptly stop taking amitriptyline, since it can lead to symptoms such as nausea, vomiting, lack of appetite, headaches, dizziness, anxiety, chills, insomnia.These signs do not indicate which developed depending on the drug and will soon pass.But they can be avoided if stop taking amitriptyline and gradually, in accordance with the recommendations of the doctor.

Read more What is depression and why it occurs