Hypnotics are always in high demand.Today, when the stress and long-term neuro-psychological stress have become constant companions of mankind, the number of people suffering from insomnia, increased significantly.This makes the drug manufacturers to develop new means for the treatment of insomnia.
mechanism of action imovan
imovan (INN - zopiclone) - This hypnotic, also has a soothing, relaxing muscles, and anticonvulsant effect.
These effects are due to its effect on the receptors sensitive to gamma-aminobutyric acid (GABA) - neurotransmitter (substance with which transmit nerve impulses) involved in the inhibition in the central nervous system.Imovan reduces sleep time, reduces the frequency of nighttime awakenings, increased duration of sleep, improves the quality of sleep and awakening (morning after his admission on the eve of no drowsiness and weakness).
Getting used to imovanu develops gradually, is considered a safe treatment for a month, but manufacturers say the lack of depen
imovan If ingestion is rapidly absorbed, reaching maximum concentration in blood after 1.5-2 hours.Absorption of the drug is independent of food intake.In the liver, the drug is decomposed and decomposition products are excreted in urine and feces.Repeated dose accumulation of the drug or its breakdown products in the body does not occur.
Indications and contraindications for use
imovan prescribed for the treatment of various types of insomnia in adults.Also included difficulty falling asleep, frequent nocturnal awakenings, early awakenings.At the time insomnia is recommended course of treatment no more than five days, with heavy stress - two to three weeks.Chronic insomnia should be treated under medical supervision.The drug is taken immediately before going to bed, sleep duration Dreams: how to understand our dreams thus should not be less than six hours, otherwise the possible emergence of anterograde amnesia (forgetting that occurs immediately after waking up).
Reception imovan contraindicated:
- are hypersensitive to the components of the drug;
- in severe muscle weakness (myasthenia gravis);
- with severe respiratory distress syndrome and sleep apnea (temporary cessation of breathing during sleep);
- with severe hepatic insufficiency;
- during pregnancy and breast- Breastfeeding - a personal choice breast;
- under the age of 18 years (clinical trials on children have not been conducted);
- during prolonged depression (depressed mood).
Not recommended simultaneous imovan with alcohol and other drugs, psychotropic (affecting the central nervous system) actions, as well as with erythromycin.
Course duration should not exceed a month, otherwise we can not exclude addiction to the drug.The risk of addiction increases with the dose and the background of alcohol and other drugs, as well as just a joint application imovan with alcohol and other psychotropic drugs Psychotropic drugs and their effect on the brain .When forming, depending on the possible emergence of imovan withdrawal, so it is better to cancel, gradually reducing the dose.
If the kidney function take half the recommended dose.
During treatment imovanom better refrain from driving and other work requiring the coordination of movements.
Side effects and overdose
When receiving imovan may cause the following side effects:
- from the gastrointestinal tract - dry and bitter taste in the mouth, nausea, diarrhea, and sometimes - transient disturbances of liver function;
- of the central nervous system - dizziness, headache, drowsiness after waking, memory impairment;rarely have side effects such as nightmares, irritability Irritability - Try to control your mood , confusion, hallucinations, aggressiveness, confusion, depressed mood, incoordination, depression, inappropriate behavior with the possible development of memory loss;
- allergic reactions - skin rash, itching, rarely - angioneurotic edema and anaphylactic shock;
- appearance of withdrawal syndrome and insomnia after discontinuation of treatment.
Overdose manifests gain all the side effects of the drug.At the same time the patient must be washed stomach, to give a few tablets of activated charcoal (it deposited and removed from the body all the toxins) and call an ambulance - Further assistance can be provided only in a hospital.