Omeprazole and breast-feeding - have any contraindications?
Most manufacturers of the drug believe that omeprazole and lactation Breastfeeding: Breast - and no nails! incompatible.But if you read the instructions in the original drug loseku, the active substance is omeprazole, one can see that breast-feeding is not a contraindication for receiving it - the manufacturer recommends to just assign this case losek with caution.
How does Omeprazole
anti-ulcer drug omeprazole after oral administration is absorbed into the blood and comes out into the cells of the gastric glands, located in its mucosa.
Action omeprazole occurs at the cellular level - it blocks the transport of hydrogen ions and chlorine from the cells.Since the interaction of these ions is formed, hydrochloric acid, resulting in a decrease in acidity.Next omeprazole bloodstream to the liver, there is decomposed into neutral metabolites and excreted primarily in the urine and partially with bile.
Currently, the question of whether it is allocated omeprazole with human milk, and if stands, the way he acts on the baby, still not fully explored.And if the manufacturer of the original drug loseka (Swedish pharmaceutical company AstraZeneca) conducted laboratory studies of the drug in animals, the manufacturers of generics (copies of the original drug), in most cases did not conduct such studies.
From this difference in the recommendations: losek allowed to take during lactation if the testimony of life, while the other manufacturers do not risk to give such permission and recommend on timetreatment to interrupt breastfeeding.Obviously, the past is still right, as omeprazole may produce significant side effects.How is this effect of the drug will affect the baby, just do not tell anyone.
Of course, the mother may be conditions that require active treatment.Such treatment should take place only under the supervision of a doctor using drugs, which it is known that they are not allocated to human milk.The appointment of medicines, the effect of which on the organism studied enough lactating women require interruption of breastfeeding.Omeprazole is assigned to long courses (at least two weeks in a row), so after the end of treatment recovery breastfeeding is likely to be impossible.
Side effects of omeprazole
Omeprazole is generally well tolerated.However, this drug is sometimes (quite rare) can produce severe side effects, sometimes requiring hospitalization.If a woman is breastfeeding, the question arises: how to respond to omeprazole baby (of course, if omeprazole is excreted in human milk)?
Side effects of omeprazole may occur from the central and peripheral nervous system.In patients with headaches, dizziness Dizziness - if the ground is slipping from under his feet , various sensory disturbances (eg, feeling of pins and needles in the body), taste disturbances, vision.There may be weakness, drowsiness or insomnia, irritability, depressed mood, recurring confusion.Severe liver disease may develop encephalopathy - exchange-dystrophic lesions of the brain.
As you know, many children in utero, during delivery are often subject to a variety of adverse effects, which then adversely affect the central nervous system.Is it worth the risk and add another adverse factor - the possible effects on the brain child omeprazole?
Side effects when taking omeprazole may also arise on the part of the digestive system.It nausea, vomiting, constipation or diarrhea, dry mouth and a penchant for the development of stomatitis Stomatitis - to breath fresh , abnormal liver function (and, if the patient had liver problems, the violations in patients receiving omeprazole maybe very significant).Whether such side effects an infant baby man, albeit with a little finger , digestive system which has just started to function?
Finally, when taking omeprazole may develop significant changes in the blood system.In peripheral blood white blood cell count decreases (and with it impaired immunity), platelets (there bleeding) and red blood cells (anemia).
Side effects when taking omeprazole are rare, but no one knows what side effects may occur in the infant if the drug, which takes his mother is released from human milk.