absolute contraindications for the appointment of Motilium during pregnancy is not, as there was no evidence of its negative effects on the mother or fetus.However, experience with this drug during pregnancy is not and it should be used only for health reasons and on doctor's orders.
What a pregnant woman may need motilium
One of the complications of pregnancy is the early toxicosis, which is accompanied by nausea and vomiting.Some women toxicosis occurs not heavy, and vomiting is one - two times a day.Others have vomiting can wear indomitable character - a woman loses a lot of fluid and mineral salts, which leads to dehydration.This is a very dangerous condition that requires hospitalization and treatment in a hospital.
In severe and severe toxemia of pregnancy prescribe antiemetics, including Reglan Reglan : help against nausea and motilium.But they can be used only if prescribed by and under the supervision of a physician.
nausea and constipation can be confusing for a woman thro
But this condition is not usually an indication for the use of Motilium, it is removed with the help of proper nutrition Proper nutrition - basic precepts of healthy food and dosage physical activity.Motilium is not so harmless to pregnant women and should be used only for health reasons.
What dangers can arise when taking Motilium during pregnancy
mechanism of action Motilium (active substance - domperidone) is based on blocking the action of dopamine receptor - a neurotransmitter that transmits nerve excitation of nerve cells.Dopamine inhibits smooth muscle contractility of the stomach, that is in fact the same effect as progesterone Progesterone - norm and pathology .At the same time it suppresses nausea and vomiting as the stomach breaks the connection with the vomiting center.When
blocked dopamine action, locomotor activity and tone of smooth muscle of the upper regions of the gastrointestinal tract (stomach, esophagus and duodenum) increases.In the normal course of pregnancy is not usually harmful to a pregnant woman.
But if there is a threat of termination of pregnancy (usually due to a lack of progesterone), theoretically it can use Motilium strengthen as increased gastric motility can result in strengthening the friendly tone and motility of the smooth muscle of the uterus, and this is dangerous.The instructions to motilium no mention of such a danger, however, it can not be excluded, because pregnant women should not take any drugs activates the smooth muscles of the pelvic organs, including laxatives.
Motilium drug and non-toxic when taken in recommended doses usually has no side effects.But during pregnancy the operation of all organs and systems, as well as metabolic changes, so it is difficult to predict what effect a particular drug.
established that motilium can produce the following side effects:
- the part of the digestive system - dry mouth, thirst, constipation, abdominal pain Abdominal pain: Types and Symptoms , caused by spasms of the intestine;
- of the central nervous system - headache, dizziness, extrapyramidal disorders;extrapyramidal system of the brain is responsible for posture, gait, its violation may cause twitching of facial and masticatory muscles of the face (tics, lockjaw);in adults, these side effects are rare, as motilium misses the brain (does not pass the blood-brain barrier), in children as extrapyramidal disorders are more common due to the imperfections of protective systems;it is impossible to completely eliminate such side effects and during pregnancy;
- with the endocrine system - increased blood levels of prolactin;in pregnant women may cause premature secretion of breast milk;
- allergic reactions - sometimes pregnant women are allergic to the substance starts (including drugs), which she had taken without any signs of intolerance.
difficult to predict how it will affect a pregnant woman or that drug.That is why all instructions to motilium says that it can appoint only for health reasons, that is when the intended benefits to the mother's body than the potential harm to the fetus.