Duspatalin - children under 18 are not recommended
in accordance with the instructions, developed by the manufacturer, Duspatalin not recommended for children under the age of 18, as there are no data on the safety and efficacy of this drug in children.However, today there is evidence that Duspatalin used to treat children with various chronic diseases of the digestive system.
How does Duspatalin on the child
Duspatalin refers to a group of drugs with antispasmodic myotropic action, that is, it acts directly on the smooth muscles of the digestive system.It is believed that the action of its double, as it does not cause a complete suppression of the motor activity of smooth muscle, including normal.A feature Duspatalin Duspatalin - helps, not hurts is the fact that he has a selective action on the sphincter of Oddi - the circular muscle surrounding the end portions of the common bile and pancreatic ducts, as well as their common channel after the merger in its placepassing through the wall of the duodenum.
Duspatalin ten times higher than a papaverine ability to relax the sphincter of Oddi.However, he does not act on the cholinergic system (the transmission of nerve excitation of nerve cells in the smooth muscle fibers using the neurotransmitter acetylcholine), and therefore does not cause side effects such as dry mouth, blurred vision, tachycardia, urinary retention, constipation and muscle weakness.This allows you to apply Duspatalin children with accompanying symptoms such diseases like urinary retention, and increased intraocular pressure.
Duspatalin mechanism of action is associated with a decrease in intracellular calcium and sodium in the smooth muscle cells.In its application it relieves spasms of smooth muscles, while maintaining its normal tone and motor activity.In addition, the recharge Duspatalin reduces intracellular calcium stores, it contributes to short-term exit of potassium ions out of the cell and prevents the full reduction in the tone of smooth muscles, which distinguishes the action from the actions of other Duspatalin Myotropic antispasmodics (eg, papaverine papaverine - for pain caused by spasmssmooth muscle and shpy), causing prolonged complete relaxation of smooth muscles of the digestive system.
But it Duspatalin as other myogenic antispasmodics, has a relaxing effect on the lower esophageal sphincter, so it is not recommended at reflux (reverse flowing food) from the stomach into the esophagus.
Which diseases in children is used Duspatalin
Duspatalin is used in the treatment of sphincter of Oddi dysfunction (DSO - current violation of bile and pancreatic juice at the level of connection of the gall and pancreatic ducts) in children.This removes Duspatalin characteristic DSO abdominal pain Abdominal pain: Types and Symptoms .And as the DSO is often combined with other disorders of the digestive system, also related to the peculiarities of the functioning of smooth muscle, this leads to an overall improvement in digestion and relieving pain in a child with combined pathology of the gastrointestinal tract in children.These comorbidities of the gastrointestinal tract in children is often what leads to the appointment of a large number of drugs that have sometimes adverse effects on other organs and systems of the body of the child.
is often found in childhood Associated inflammatory processes in the stomach, duodenum, gall bladder Gall bladder: structure and function and biliary tract, which also combined with spasm of the sphincter of Oddi.These diseases always occur with pain, nausea and vomiting.
For the treatment of such comorbidity prescribe complex treatment helps to relieve inflammation of the mucous membrane of the stomach and duodenum, improve motor-evacuation activity of the stomach and intestines, the restoration of the outflow of bile.
This is quite a difficult task, given the fact that a large number of drugs can bring harm to the baby.Therefore, to reduce spasms and while maintaining the normal tone and motility of the smooth muscle of the digestive apparatus of the child in the complex treatment began to introduce Duspatalin.This medication is able to replace several other drugs that affect the individual organs of digestion.
Clinical experience shows that under medical supervision it can be used in children from the age of two.The course of treatment (adjuvant therapy) is an average of about two weeks.This pain, nausea and vomiting are an average of two days earlier than with conventional treatment and does not require the appointment of additional drugs to treat violations of the biliary tract.Side effects and complications when used Duspatalin to treat children have been identified.
Duspatalin used for the treatment of various dysfunctions of the gastrointestinal tract in children, but so far only as an experiment.Appoint such treatment can only physician.