It is a rare disease with a favorable prognosis is not always that develops in patients with congenital disorders of immunity (primary immunodeficiencies) in children from birth.These children need to constantly observe and be treated in accordance with established procedures.
What is this disease
chronic generalized (granulomatous) candidiasis - is a disease that occurs in children with severe congenital immune disorders, as well as in violation of the parathyroid and other glands.It starts with oral candidiasis Oral candidiasis - affects not only children (thrush), and then captures all the new spaces of the mucous membranes, skin and internal organs.If such a child is not receiving adequate treatment, the candida can cause his death.
generalized candidiasis may occur in different ways.But more often it begins with oral thrush is not amenable to conventional treatment.Thrush begins with the oral mucosa, and is manifested as redness, swelling Prevention and treatment of edema - it is important to understand the root cause of oral mucosa and the appearance of her typical cheesy raids that first quickly removed with a spatula, and then fused with mucousshell and become a dense film, which are found in removing the sores.Gradually candidiasis passes to area tongue, gums, palate, throat, tonsils.In the corners of the mouth appear stubbornly passing perleches (candida cheilitis), and covered with coarse language folds.
Thrush can also occur somewhat differently, with marked redness and dryness of the oral mucosa, which appear whitish spots merging with each other.Language is sometimes a distinctive appearance by increasing the papillae and fungal filaments black covering language - "black hairy tongue."This state of the mucous membrane of the mouth makes it difficult to breast- Breastfeeding - a personal choice and causes it to lag behind in the physical and psychological development.
immunodeficiency condition is always accompanied by a variety of bacterial infections, about which the child being treated with antibiotics Antibiotics - whether they will help you in the foreseeable future? .And it further enhances the existence of candidiasis, and contribute to its spread to other organs (generalization).It affects the skin, nails, scalp.On the face, scalp, trunk and limbs appear red scaly patches with sealing (infiltration) in the base (granulomatous foci), as well as elements of the skin such as papules and bumps.All these elements form the first completed rough crusts and then scarring and lead to the emergence of centers of baldness on the scalp and ugly scars on the smooth skin.
suffer and nails: they thicken, deform, change color, and nail ridges become swollen.
also developing signs of visceral candidiasis - internal organ.This can be candida lung lesions, gastrointestinal tract, liver, and kidney.As well as a bacterial infection in immune deficiency "never sleeps" inflammatory processes often are mixed fungal-bacterial in nature.When esophageal candidiasis in the child's condition worsens, develop swallowing difficulties, as on the walls of the esophagus grow films often completely covering the lumen of the esophagus.Intestinal lesions give rise to persistent diarrhea, while in the stool is common to see blood.
generalized candidiasis is usually accompanied by severe course and anemia, fever, decrease the density of the long bones (osteoporosis), recurrent bronchitis and pneumonia, diarrhea and others.
Diagnosis and treatment
Diagnosis is based on typical clinical and laboratory investigations, including investigations of the state of immunity.When visceral lesions conducted research on the state of internal organs - X-ray, ultrasound, endoscopy.
treatment of generalized candidiasis should be carried out only in the hospital, because the child can be difficult.Antifungals applied dosage for parenteral (bypassing the gastrointestinal tract) administration.When you join a bacterial infection antibiotics are prescribed.Be sure we treat immune disorders, sometimes we have to do for life.
generalized candidiasis - a fungal disease is severe, difficult to treat.