Vasculitis in children - especially their
Children are most often found certain types of systemic vasculitis, which are much less likely to occur in adults.The manifestations of systemic vasculitis in children also have their own characteristics, due to which they are called children or juvenile systemic vasculitis.
features of systemic vasculitis in children
Systemic vasculitis - an inflammation of the infectious nature in the walls of blood vessels.For different vasculitis usually affects small, medium or large blood vessels.These diseases are rare.Their nature usually has a complex infectious-allergic and genetic basis.But until now, systemic vasculitis is one of the most unexplored diseases.For the development of these diseases usually requires a genetic predisposition, a tendency to allergies, frequent infections and the use of various drugs.
in children is most common hemorrhagic vasculitis Vasculitis - when blood vessels refuse to work (kapillyarotoksikoz's disease, Henoch - Schonlein purpura).In addition, they can develop Kawasaki syndrome, knotted (nodular) polyarteritis, nonspecific aortoarteriit.These vasculitis belong to the group of children or juvenile diseases
sometimes found in children and other vasculitis: Wegener's granulomatosis, Chardjui-Strauss syndrome, Behcet's syndrome.
Kawasaki syndrome in children
Kawasaki syndrome or mucous - kozhnozhelezisty syndrome - a disease peculiar to young children.This affects the walls of medium-sized blood vessels.Specific manifestations of this disease are a rash, fever and inflammation of the lymph nodes.Kawasaki syndrome may be complicated by inflammation of the joints and the heart.
Why is this disease begins in children.Today, no one knows.It is possible that a precipitating factor is a viral disease.More common in boys aged from a few months to four or five years, but the disease is found in teens and adults.There are family history of the disease, suggesting a hereditary factor.
disease begins with high fever, weakness, drowsiness.Then, on the skin and mucous membranes appear red maculopapular rash.At the same time noted the appearance of dry red tongue, cracked lips Chapped lips - lips properly look after , redness in the throat, irritation and redness of the sclera of eyeballs.The palms and soles become red and swollen.Increases and becomes painful lymph nodes in the neck.
After two or three weeks after the onset of the rash passes, the lymph nodes are reduced in size, and the skin on the hands and feet begins to peel off.But this time may develop complications from the heart, which can have serious consequences.In addition, the possible development of arachnoiditis (inflammation of the meninges), arthritis (joint inflammation) and gall bladder, which are reversible.
polyarteritis nodosa in children
polyarteritis nodosa (knotty periarteritis) - a disease in which the inflammatory process is developing in the walls of the small and medium-sized arteries.In the affected artery aneurysm formation (expansion thinning of the arterial wall).The aneurysms there is stagnation of blood to form clots that clog the vessel lumen, disrupting the blood supply to an organ.
believed that the starting point for the onset of the disease can be vaccinated, drugs, viruses causing chronic hepatitis Hepatitis - the scourge of our time , as well as other viral infections.Also, it matters that a child of any allergies.
disease begins acutely with high fever, muscle-joint pain (pain and swelling of the joints, pain in the calf muscles), rash.The temperature then rises to very high numbers, then falls, which is accompanied by drenching sweat.Very fast depletion occurs, the child loses a significant body weight.The skin appears bluish rash characteristic of marbling or tree branches.They can be very bright, but then gradually fade.Furthermore, there nodular rash.
thrombosis occurs when blood vessels in the skin and mucous membranes, which may be accompanied by the emergence of areas of necrosis (tissue necrosis) with subsequent ulceration.
central nervous system causing severe headaches, vomiting, and sometimes convulsions, visual disturbances.With the defeat of the gastrointestinal tract nausea, vomiting, severe abdominal pain paroxysmal Abdominal pain: Types and Symptoms .Such lesions may be complicated by rupture of the intestinal wall and peritonitis.It is also possible kidney damage in the form of glomerulonephritis and cardiac complications.
nonspecific aortoarteriit children
nonspecific aortoarteriit (Takayasu's disease, pulseless disease) - manifested in defeat large blood vessel - the aorta and its branches, which results in impaired blood supply to various organs, including the absence of a pulse.This disease is more common in girls aged 10 to 15 years, but it also occurs in preschool children, and the case for its more severe.
Takayasu's disease can be complicated by aneurysm thoracic and abdominal aorta and coronary vessels of the heart to slow its progressive occlusion (decrease in lumen) that gives rise to attacks of angina and myocardial infarction.
Vasculitis in children is more severe and require timely and appropriate medical care.