Ampicillin is not contraindicated during pregnancy, but to appoint him standing with caution, as the impact on the body of the pregnant women of different drugs studied enough.Especially cautiously this drug should be administered during the first trimester of pregnancy.
Ampicillin in the first trimester of pregnancy (the first twelve weeks), like any other drug should be used with great caution and only in the event that his appointment is required for health reasons.
This attitude to drugs in the first trimester of pregnancy is necessary, because in this period is laying the tissues and organs of the embryo.Any substance that is able to interfere with the metabolic processes may cause a violation of a bookmark that will result in developmental abnormalities (malformations) in a newborn.Ampicillin in this respect is no better and no worse than any other substance.
developmental anomalies it usually does not cause toxic effects on the fetus have not, but such complica
However, if the condition of the woman requires antibiotic, they are assigned based on indications, contraindications and side effects of these drugs.It allowed for the use of antibiotics during pregnancy Antibiotics - whether they will help you in the foreseeable future? include ampicillin.
In the second trimester of pregnancy (thirteen to twenty-four weeks) the state of health of the pregnant woman is improving, but the immune system it is reduced.Therefore, it is possible the development of infectious and inflammatory diseases.Most of these diseases develop in the nose, throat and upper respiratory tract.In this disease in most cases begins with the viral infection and immunity have been reduced in pregnant women are often joined to viral bacterial infections.When to stop such an infection home remedies can not, then appointed antibiotics, including ampicillin.Ampicillin and inflammatory processes in the kidneys and urinary tract - cystitis and pyelonephritis, which often occur in pregnant women.
second trimester appointment of ampicillin is not so dangerous.
of its side effects, trouble can deliver mainly disorders of the gastrointestinal tract.They may take the form of dysbiosis, digestive disorders accompanied by signs - bloating, alternating constipation and diarrhea, pain during bowel.During long-term courses of treatment may "earn" and intestinal inflammation - colitis.Ampicillin may have a negative effect on the liver, which manifests itself in violation of its transitory function.Sometimes such violations appear icteric staining of the skin.
Furthermore, ampicillin has the side effect of reducing the number of leukocytes in the blood, including the complete or almost complete disappearance of the granular leukocytes (agranulocytosis).This is a dangerous condition for a pregnant woman, because it speaks of marked decrease in immunity.Immunosuppression during pregnancy often leads to the development of genital candidiasis genital candidiasis: possible severe complications - thrush, from which then so hard to get rid of.Therefore, to use ampicillin alone a pregnant woman can not even be in this relatively quiet period.
third trimester of pregnancy
In the third trimester of pregnancy (with the twenty-fifth week before delivery) threat to the health of women and the fetus from the medication increase again.Admission ampicillin except discomfort on the part of the gastrointestinal tract and decreasing immunity Immunity - the types and characteristics of children in adult , creates another and the threat of bleeding as a side effect of reducing blood clotting and reduce the amount of blood platelets Platelets - what are they for the body? .And before birth is quite useless.
There is also the threat of anemia - Ampicillin suppresses the formation of red blood cells, and their number in the blood decreases.And it was the red blood cells, which contain hemoglobin, carry a maternal and fetal tissues of oxygen, so when anemia (especially if it is expressed much) is almost always present signs of feto-placental insufficiency, which affects mainly the central nervous system of the fetus.
Together, the side effects of ampicillin can create significant problems in the third trimester of pregnancy.However, the correct assignment of the drug brings benefits - saves a pregnant woman from infection and prevents its penetration to the fetus, that is, the development of intrauterine infection.