During pregnancy, women are not allowed to make their own, even the safest medications that do not have a toxic effect on the body.This rule must be observed at all times, as during pregnancy hormonal changes and metabolism improves metabolism and losing weight without dieting , which could significantly alter the body's response to any foreign substance.
mechanism of action
Diflucan Diflucan (INN - fluconazole) - is an antifungal drug which has a selective effect on cells sensitive to it mushrooms: it inhibits the synthesis of certain vital substances fungal cells, causing them towithering away.
Diflucan - this is a very effective drug, it has a broad spectrum antifungal activity.Sensitivity to show him the majority of pathogenic fungi, including causing severe fungal infections, such as generalized candidiasis, cryptococcosis, fungal skin diseases, including deep mycoses (trichophytosis and microsporia) and others.Naturally, such an effective drug has side-effects and contraindicat
Side effect of fluconazole is manifested in the form of headaches, dizziness, changes in taste and sometimes even appear jerking.There may be as nausea, vomiting, diarrhea, abdominal distension (bloating), abdominal pain Abdominal pain: Types and Symptoms , abnormal liver function, irregular heartbeat, hair loss, changes in the blood, leading to decreased immunityand excessive bleeding (decreased numbers of white blood cells and platelets), and various metabolic disorders and allergic reactions.
Diflucan is not allowed to appoint at hypersensitivity to its components, feeding the baby Breastfeeding - a personal choice feeding, simultaneous applicationdrugs that could affect heart rate (e.g., cisapride - drug enhances motility of the gastrointestinal tract) and some antihistamines (e.g., terfenadine).
recommended to be careful in appointing Diflucan in the human liver, heart rhythm disturbances and pregnancy.
How Diflucan operates on a pregnant woman
Absolutely nobody knows it.In order to answer this question, Diflucan should pass first laboratory tests on animals, then clinical trials in pregnant women.Laboratory tests on animals were performed in accordance with existing international rules and did not reveal any contraindications to the use of the drug in pregnant women.
Clinical trials of the drug have not been conducted, therefore the safety of Diflucan for pregnant women has not been proved.In addition, in the medical literature described cases of teratogenicity Diflucan, which manifests itself in the form of multiple congenital malformations in newborns whose mothers had for several months been treated with fluconazole (it is the main active ingredient of Diflucan) in high doses for severe fungal diseases.Nevertheless, a clear link between these abnormalities and reception of fluconazole was not established.
therefore given instructions that pregnant women Diflucan can be used only in extreme cases when there is a threat to her life.And such a situation may arise, for example, the development of fungal meningitis, generalized candidiasis (destruction of all organs and systems of fungi genus Candida), severe candidiasis visceral, deep fungal infections of the skin and so on.All of these fungal skin lesions are dangerous not only for women but also to the fetus, as they may cause fetal infection.For such cases, the instructions for use of medicines is written that the drug should not be administered during pregnancy except in cases of severe and potentially life-threatening fungal infections, when the expected benefit of treatment exceeds potential risk to the fetus.
In light of fungal infections, such as thrush (fungal attack of Candida mucosal genital and oral) pregnant women are prescribed other medications that can be administered during pregnancy, for example, pimafutsin Pimafucin - help in difficult times .
Independently pregnant woman can not use any anti-fungal drugs, even if they appear to be quite safe to her.The decision whether or not to prescribe Diflucan this or that women taking only her doctor.