The instructions to trentalu developed by the manufacturer (Indian farmatsevitcheskoy Aventis Pharma) stated that trental during pregnancy is contraindicated.However, this drug is widely used for the treatment of various circulatory disorders from occurring in this difficult for women period.
Circulatory disorders that may occur during pregnancy
Any circulatory disorders during pregnancy may pose a risk to the fetus.In the second half of pregnancy in women can begin this complication as late toxemia, or preeclampsia pregnancy.This condition is closely related to the stagnation of blood in the very small blood vessels - the capillaries, causing first swelling (fluid propotevaet through the walls of blood vessels), and then changes in the kidney (high blood pressure and protein in the urine), and finally by the headbrain (headache, convulsions, coma).
Today, all pregnant women are under the constant supervision of an obstetrician-gynecologist of female consultation, so severe gestosis are
Another cause circulatory disorders during pregnancy is fetoplacental insufficiency (FPI).It is poor circulation in the mother - placenta - fetus.Usually, it is caused by persistent spasm of blood vessels of the placenta, which is why the fetus does not receive oxygen and nutrients.Moreover, against the stagnation of blood in the blood vessels of the placenta may form thrombi.With little FPN child may have perinatal damage the nervous system and a mild developmental delay, with significant blood circulation in the placenta - severe brain injury, premature birth and stillbirth.
what purpose trental administered during pregnancy
during pregnancy are particularly important drugs that restore normal blood circulation,One such drug is Trentalum.Producers of this drug is not recommended for use during pregnancy because of the fact that no adequate clinical studies conducted its effect on pregnant women.However, in practice, this drug is widely used, as in this case, the potential benefits from its use exceeds the potential risk to the fetus.Of course, this drug appoint a pregnant woman (like all drugs) should be a doctor.
Trental promotes dilation of blood vessels of the placenta, prevents platelets from sticking together (prevention of blood clots) and reduce blood viscosity, red blood cells returns normal configuration, whereby they can carry more oxygen to the tissues.
This action helps reduce circulatory disorders and preeclampsia and feto-placental insufficiency.Trental is usually administered in a long-acting tablets (trental - 400), which is enough to take once a day.The duration of treatment prescribed by a doctor.
With rapidly developing circulatory failure in pregnant women trental can be administered intravenously.
trental In some cases, pregnant women are not assigned
Trental pills not prescribed to pregnant women with peptic ulcer disease - it irritates the stomach lining.In addition, trental not indicated for increased bleeding or suspected internal bleeding (such as bleeding in the retina of the eye).After 33 weeks of pregnancy trental try not to prescribe, as it can lead to bleeding during delivery or cesarean section.Not assigned trental well as porphyria (congenital disorders sharing, accompanied by photophobia) and hypersensitivity to trentalu and other xanthine derivatives (eg caffeine).
For intravenous trental contraindications include cardiac arrhythmias, arteriosclerosis expressed Atherosclerosis - a chronic disease of the arteries cardiac or cerebral arteries, very low blood pressure.
In most cases trental well tolerated, but there are side effects.Especially dangerous for a pregnant woman side effects of the cardiovascular system, such as a sharp drop in blood pressure Blood pressure - dangerous if his swing? , tachycardia, cardiac arrhythmias, heart pain pain in the heart - always consult a physician , the progression of angina.
Less common side effects on the central nervous system - headache, dizziness Dizziness - if the ground is slipping from under his feet , a constant feeling of anxiety, insomnia, sudorzhnaya readiness.
Most changes occur from the gastrointestinal tract, liver and biliary tract, which appear dry mouth, violation of appetite, constipation atonic (violation of motor activity of the intestine, which is carried heavily pregnant, and so who are prone to constipation), aggravationdiseases of the gallbladder and bile ducts of the liver.
There are also visual disturbances, changes in the blood (decrease in the number of blood cells and reducing its clotting ability), redness of the skin in the form of a "tide", swelling, allergic reactions.